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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Babe Ruth* | 518 | 1914-1935 | |
| 2 | Hank Aaron* | 500 | 1954-1976 | |
| 3 | Reggie Jackson* | 465 | 1967-1987 | |
| 4 | Mel Ott* | 445 | 1926-1947 | |
| 5 | Gary Sheffield# | 433 | 1988-2001 | |
| 6 | Darryl Strawberry | 363 | 1983-2000 | |
| 7 | Frank Robinson* | 336 | 1956-1976 | |
| 8 | Bobby Bonds | 321 | 1968-1981 | |
| 9 | Dwight Evans | 307 | 1972-1992 | |
| 10 | Al Kaline* | 296 | 1953-1974 | |
| 11 | Juan Gonzalez# | 288 | 1990-2000 | |
| 12 | Dave Parker | 273 | 1973-1989 | |
| 13 | Phil Plantier# | 264 | 1988-1999 | |
| 14 | Rocky Colavito | 262 | 1955-1968 | |
| 15 | Roger Maris | 261 | 1957-1968 | |
| 16 | Jesse Barfield | 259 | 1981-1998 | |
| 17 | Chuck Klein* | 249 | 1928-1944 | |
| 18 | Raul Mondesi# | 246 | 1991-2001 | |
| 19 | Dave Winfield | 242 | 1973-1992 | |
| 20 | Roberto Clemente* | 240 | 1955-1972 | |
| 21 | Bill Nicholson | 235 | 1936-1953 | |
| 22 | Harold Baines | 234 | 1980-1999 | |
| 23 | Brian Giles# | 214 | 1991-2001 | |
| 24 | Johnny Callison | 204 | 1958-1973 | |
| 25 | Jack Clark | 200 | 1975-1993 | |
| 26 | Dante Bichette# | 198 | 1989-2001 | |
| 27 | Rusty Staub | 192 | 1963-1985 | |
| 28 | Tom Brunansky | 186 | 1981-1996 | |
| 29 | Carl Furillo | 177 | 1946-1960 | |
| 29 | Tony Oliva | 177 | 1962-1976 | |
| 31 | Ken Singleton | 176 | 1970-1984 | |
| 32 | Tommy Henrich | 169 | 1937-1950 | |
| 33 | Reggie Smith | 167 | 1966-1982 | |
| 34 | Jackie Jensen | 165 | 1950-1961 | |
| 35 | Harry Heilmann* | 164 | 1914-1932 | |
| 36 | Hank Bauer | 163 | 1948-1961 | |
| 37 | Ruben Sierra | 156 | 1986-1998 | |
| 38 | Jeff Burroughs | 153 | 1970-1985 | |
| 39 | Chili Davis | 152 | 1981-1998 | |
| 40 | Jose Canseco# | 151 | 1985-2000 | |
| 40 | Wally Post | 151 | 1949-1964 | |
| 42 | Jay Buhner | 148 | 1987-2000 | |
| 43 | Albert Belle# | 144 | 1988-2001 | |
| 44 | Andre Dawson | 142 | 1976-1991 | |
| 45 | Tony Conigliaro | 140 | 1964-1975 | |
| 45 | Sixto Lezcano | 140 | 1974-1985 | |
| 47 | Shawn Green# | 138 | 1992-2001 | |
| 48 | Stan Musial* | 136 | 1941-1963 | |
| 49 | Phil Nevin# | 134 | 1994-2001 | |
| 50 | George Bell | 133 | 1981-1995 | |
| 51 | Babe Herman | 132 | 1926-1945 | |
| 52 | Enos Slaughter* | 130 | 1938-1959 | |
| 53 | Vladimir Guerrero# | 129 | 1996-2001 | |
| 54 | Tony Gwynn | 127 | 1982-2000 | |
| 54 | Willie Kirkland | 127 | 1958-1966 | |
| 54 | Sam Thompson* | 127 | 1885-1906 | |
| 57 | Vinny Castilla# | 124 | 1991-2001 | |
| 58 | Vic Wertz | 122 | 1947-1963 | |
| 59 | Frank Howard | 121 | 1958-1973 | |
| 60 | Bo Jackson# | 120 | 1986-2001 | |
| 61 | Gavvy Cravath | 116 | 1908-1920 | |
| 61 | Ellis Valentine | 116 | 1975-1985 | |
| 63 | Paul Waner* | 113 | 1926-1944 | |
| 64 | Ken Griffey Jr.# | 111 | 1988-2001 | |
| 65 | Bob Allison | 108 | 1958-1970 | |
| 65 | Mike Marshall | 108 | 1981-1996 | |
| 65 | Claudell Washington | 108 | 1974-1991 | |
| 68 | Al Cowens | 107 | 1974-1986 | |
| 68 | Orlando Merced# | 107 | 1988-2001 | |
| 70 | J.D. Drew# | 106 | 1997-2001 | |
| 70 | Willard Marshall | 106 | 1942-1955 | |
| 70 | Bobby Murcer | 106 | 1965-1983 | |
| 73 | George Hendrick | 105 | 1971-1988 | |
| 74 | Bruce Campbell | 104 | 1930-1942 | |
| 75 | Ron Northey | 103 | 1942-1957 | |
| 76 | Preston Wilson# | 102 | 1996-2001 | |
| 77 | Tony Armas | 101 | 1976-1987 | |
| 78 | Jim King | 100 | 1955-1967 | |
| 79 | Michael Tucker# | 99 | 1996-2001 | |
| 80 | Jim Northrup | 97 | 1964-1975 | |
| 81 | Dan Ford | 94 | 1975-1985 | |
| 81 | Brian Jordan# | 94 | 1988-2001 | |
| 83 | Bobby Abreu# | 93 | 1993-2001 | |
| 83 | Kirk Gibson | 93 | 1979-1995 | |
| 83 | Bernard Gilkey# | 93 | 1989-2001 | |
| 83 | Rafael Palmeiro# | 93 | 1986-2001 | |
| 87 | Ival Goodman | 91 | 1935-1944 | |
| 87 | Larry Walker# | 91 | 1989-2001 | |
| 89 | Marty Cordova# | 88 | 1992-2001 | |
| 89 | Mike Tiernan | 88 | 1887-1899 | |
| 91 | Ollie Brown | 87 | 1965-1977 | |
| 92 | Felipe Alou | 85 | 1958-1974 | |
| 93 | Kiki Cuyler* | 84 | 1921-1938 | |
| 93 | Mike Davis | 84 | 1980-1993 | |
| 95 | Wally Moses | 82 | 1935-1951 | |
| 95 | Larry Parrish | 82 | 1974-1989 | |
| 97 | Lance Berkman# | 79 | 1998-2001 | |
| 98 | Dave Henderson | 78 | 1981-1994 | |
| 98 | Jim Rice* | 78 | 1974-1994 | |
| 100 | Craig Wilson# | 77 | 1996-2001 |
