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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | IP | YEAR | Open Postseason Career Leaderboard |
|---|---|---|---|---|
| 1 | Bob Caruthers | 71.0 | 1887 | |
| 2 | Charlie Getzein | 58.0 | 1887 | |
| 3 | Elton Chamberlain | 44.0 | 1888 | |
| 3 | Deacon Phillippe | 44.0 | 1903 | |
| 5 | Lady Baldwin | 42.0 | 1887 | |
| 6 | Fernando Valenzuela | 40.0 | 1981 | |
| 6 | Pedro Martinez# | 40.0 | 1996 | |
| 6 | Randy Johnson# | 40.0 | 1997 | |
| 9 | Ed Crane | 38.0 | 1889 | |
| 9 | Bruce Hurst | 38.0 | 1986 | |
| 11 | Adonis Terry | 37.0 | 1889 | |
| 12 | Jerry Reuss | 36.0 | 1981 | |
| 12 | Roger Clemens# | 36.0 | 1997 | |
| 12 | Curt Schilling# | 36.0 | 1995 | |
| 12 | Jim McCormick | 36.0 | 1885 | |
| 16 | Chris Carpenter# | 35.0 | 1998 | |
| 16 | Tom Lovett | 35.0 | 1890 | |
| 16 | Bill Dinneen | 35.0 | 1903 | |
| 16 | Silver King | 35.0 | 1888 | |
| 16 | Tim Keefe* | 35.0 | 1888 | |
| 21 | Doug Drabek# | 34.0 | 1998 | |
| 21 | Roger Clemens# | 34.0 | 1986 | |
| 21 | Cy Young* | 34.0 | 1903 | |
| 21 | James Baldwin# | 34.0 | 1995 | |
| 21 | Luis Tiant | 34.0 | 1975 | |
| 26 | Charlie Hough | 33.0 | 1988 | |
| 26 | Carl Pavano# | 33.0 | 1998 | |
| 26 | Pete Conway | 33.0 | 1887 | |
| 26 | Burt Hooton | 33.0 | 1981 | |
| 30 | Kenny Rogers# | 32.0 | 1997 | |
| 30 | Orel Hershiser | 32.0 | 1994 | |
| 30 | Tom Glavine# | 32.0 | 1990 | |
| 30 | George Mullin | 32.0 | 1909 | |
| 30 | Bob Welch | 32.0 | 1989 | |
| 35 | Tom Seaver* | 31.0 | 1973 | |
| 35 | Charlie Leibrandt | 31.0 | 1985 | |
| 35 | Wilson Alvarez# | 31.0 | 1994 | |
| 35 | Frank Viola | 31.0 | 1987 | |
| 35 | Catfish Hunter* | 31.0 | 1972 | |
| 35 | Terry Mulholland# | 31.0 | 1989 | |
| 35 | Silver King | 31.0 | 1887 | |
| 35 | John Clarkson* | 31.0 | 1886 | |
| 35 | Kevin Brown# | 31.0 | 1994 | |
| 44 | Mark Langston | 30.0 | 1991 | |
| 44 | John Tudor | 30.0 | 1985 | |
| 44 | Tom Glavine# | 30.0 | 1993 | |
| 44 | Kirk Rueter# | 30.0 | 1998 | |
| 44 | Don Sutton* | 30.0 | 1974 | |
| 49 | Catfish Hunter* | 29.0 | 1973 | |
| 49 | Jeff Suppan# | 29.0 | 1996 | |
| 49 | Alex Fernandez# | 29.0 | 1998 | |
| 49 | Mike Jeffcoat | 29.0 | 1990 | |
| 49 | Mike Torrez | 29.0 | 1977 | |
| 49 | Dave Stewart | 29.0 | 1989 | |
| 49 | Dave Foutz | 29.0 | 1885 | |
| 49 | Rick Aguilera | 29.0 | 1988 | |
| 49 | Jack Stivetts | 29.0 | 1892 | |
| 58 | Danny Cox | 28.0 | 1987 | |
| 58 | Warren Spahn* | 28.0 | 1958 | |
| 58 | Christy Mathewson* | 28.0 | 1912 | |
| 58 | Steve Avery# | 28.0 | 1991 | |
| 58 | Pete Vuckovich | 28.0 | 1982 | |
| 58 | Darryl Kile# | 28.0 | 1997 | |
| 58 | Jim Abbott# | 28.0 | 1995 | |
| 65 | Don Gullett | 27.0 | 1975 | |
| 65 | Steve Rogers | 27.0 | 1981 | |
| 65 | Pedro Astacio# | 27.0 | 1995 | |
| 65 | David Wells# | 27.0 | 1995 | |
| 65 | Ben McDonald# | 27.0 | 1996 | |
| 65 | Tom Glavine# | 27.0 | 1991 | |
| 65 | Steve Carlton* | 27.0 | 1980 | |
| 65 | Jeff Fassero | 27.0 | 1996 | |
| 65 | Bob Gibson* | 27.0 | 1968 | |
| 65 | Lew Burdette | 27.0 | 1957 | |
| 65 | Christy Mathewson* | 27.0 | 1905 | |
| 65 | Roy Halladay# | 27.0 | 2000 | |
| 65 | Babe Adams | 27.0 | 1909 | |
| 65 | Bob Gibson* | 27.0 | 1967 | |
| 65 | Bob Gibson* | 27.0 | 1964 | |
| 65 | Waite Hoyt* | 27.0 | 1921 | |
| 65 | Cy Young* | 27.0 | 1892 | |
| 65 | Mickey Lolich | 27.0 | 1968 | |
| 65 | Red Faber* | 27.0 | 1917 | |
| 65 | Dave McNally | 27.0 | 1969 | |
| 65 | Hippo Vaughn | 27.0 | 1918 | |
| 65 | Stan Coveleski* | 27.0 | 1920 | |
| 65 | Christy Mathewson* | 27.0 | 1911 | |
| 65 | Jack Coombs | 27.0 | 1910 | |
| 65 | Bob Ojeda | 27.0 | 1986 | |
| 90 | David Cone# | 26.0 | 1994 | |
| 90 | Greg Swindell# | 26.0 | 1996 | |
| 90 | Bert Blyleven* | 26.0 | 1987 | |
| 90 | John Tudor | 26.0 | 1987 | |
| 90 | Scott Garrelts# | 26.0 | 1989 | |
| 90 | Charles Bender* | 26.0 | 1911 | |
| 90 | Bobo Newsom | 26.0 | 1940 | |
| 90 | Danny Jackson | 26.0 | 1985 | |
| 90 | Walter Johnson* | 26.0 | 1925 | |
| 90 | Hideo Nomo# | 26.0 | 2000 | |
| 90 | Tommy John* | 26.0 | 1981 |
