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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | K9 | YEAR | Open Postseason Career Leaderboard |
|---|---|---|---|---|
| 1 | Pedro Martinez# | 15.19 | 1992 | |
| 2 | Pedro Martinez# | 12.91 | 1998 | |
| 3 | Randy Johnson# | 12.68 | 1996 | |
| 4 | Pedro Martinez# | 11.79 | 2000 | |
| 5 | Bob Gibson* | 11.67 | 1968 | |
| 6 | Sandy Koufax* | 11.50 | 1963 | |
| 7 | Roy Halladay# | 11.33 | 2000 | |
| 8 | Sandy Koufax* | 10.88 | 1965 | |
| 9 | Jose Rijo# | 10.47 | 1992 | |
| 10 | Bob Gibson* | 10.33 | 1964 | |
| 11 | Ed Walsh* | 10.20 | 1906 | |
| 12 | Mark Langston | 10.07 | 1990 | |
| 13 | Mike Boddicker | 10.00 | 1983 | |
| 14 | Tom Seaver* | 9.95 | 1973 | |
| 15 | Jesse Barnes | 9.92 | 1921 | |
| 16 | Javier Vazquez# | 9.82 | 1999 | |
| 17 | Randy Johnson# | 9.72 | 1995 | |
| 18 | Scott Williamson# | 9.64 | 1998 | |
| 19 | Orel Hershiser | 9.60 | 1988 | |
| 20 | Hal Newhouser | 9.58 | 1945 | |
| 21 | Greg Maddux# | 9.56 | 1990 | |
| 22 | Jeff Fassero | 9.55 | 1996 | |
| 23 | Dave Righetti | 9.53 | 1981 | |
| 23 | Vic Raschi | 9.53 | 1952 | |
| 25 | Mike Scott | 9.50 | 1986 | |
| 26 | Mark Langston | 9.47 | 1993 | |
| 27 | Whitey Ford* | 9.39 | 1958 | |
| 27 | Mark Langston | 9.39 | 1991 | |
| 29 | Darryl Kile# | 9.32 | 1997 | |
| 30 | Esteban Loaiza# | 9.31 | 2000 | |
| 31 | Ron Guidry | 9.27 | 1981 | |
| 32 | Pedro Martinez# | 9.15 | 1996 | |
| 33 | Pedro Martinez# | 9.00 | 1999 | |
| 33 | Mort Cooper | 9.00 | 1944 | |
| 35 | Steve Carlton* | 8.85 | 1983 | |
| 36 | Roger Clemens# | 8.84 | 1997 | |
| 37 | Bob Gibson* | 8.67 | 1967 | |
| 38 | Jerry Koosman | 8.66 | 1973 | |
| 39 | Steve Blass | 8.64 | 1971 | |
| 40 | Tug McGraw | 8.62 | 1980 | |
| 40 | Tom Hall | 8.62 | 1972 | |
| 42 | Roger Clemens# | 8.61 | 1996 | |
| 43 | Joe Wood | 8.59 | 1912 | |
| 43 | Roger Clemens# | 8.59 | 1994 | |
| 45 | Frank Viola | 8.57 | 1994 | |
| 46 | John Clarkson* | 8.44 | 1885 | |
| 47 | Dave Dravecky | 8.40 | 1987 | |
| 47 | Nolan Ryan* | 8.40 | 1981 | |
| 49 | Mike Morgan | 8.39 | 1994 | |
| 50 | John Smoltz# | 8.38 | 1990 | |
| 51 | Hideo Nomo# | 8.31 | 2000 | |
| 52 | Mike Morgan | 8.27 | 1996 | |
| 53 | Tommy John* | 8.24 | 1977 | |
| 54 | Tug McGraw | 8.20 | 1973 | |
| 54 | Kenny Rogers# | 8.20 | 1998 | |
| 56 | John Clarkson* | 8.13 | 1886 | |
| 57 | Aaron Sele# | 8.06 | 1994 | |
| 58 | Rollie Fingers* | 8.04 | 1972 | |
| 59 | Dave McNally | 8.00 | 1969 | |
| 60 | Dave Stieb | 7.97 | 1985 | |
| 60 | Allie Reynolds | 7.97 | 1952 | |
| 60 | Alex Fernandez# | 7.97 | 2000 | |
| 63 | Jim Palmer* | 7.96 | 1971 | |
| 64 | Sal Maglie | 7.94 | 1956 | |
| 65 | Kevin Brown# | 7.89 | 1992 | |
| 66 | Matt Morris# | 7.83 | 2000 | |
| 67 | Chris Carpenter# | 7.82 | 1999 | |
| 68 | Charles Hudson | 7.79 | 1983 | |
| 68 | Jim Bibby | 7.79 | 1979 | |
| 70 | David Cone# | 7.76 | 1994 | |
| 71 | Tim Keefe* | 7.71 | 1888 | |
| 71 | Ben McDonald# | 7.71 | 1992 | |
| 73 | Jim Palmer* | 7.66 | 1970 | |
| 74 | Danny Cox | 7.65 | 1985 | |
| 75 | Max Lanier | 7.63 | 1943 | |
| 76 | Darren Oliver# | 7.61 | 1994 | |
| 77 | Andy Pettitte# | 7.59 | 1997 | |
| 77 | Randy Johnson# | 7.59 | 1998 | |
| 79 | Jeff Suppan# | 7.58 | 1996 | |
| 80 | Steve Carlton* | 7.57 | 1980 | |
| 81 | Carl Pavano# | 7.56 | 1998 | |
| 82 | Grover Cleveland Alexander* | 7.52 | 1926 | |
| 82 | Kelly Downs | 7.52 | 1989 | |
| 84 | Denny Galehouse | 7.50 | 1944 | |
| 84 | Dick Rudolph | 7.50 | 1914 | |
| 84 | Don Sutton* | 7.50 | 1974 | |
| 84 | Walter Johnson* | 7.50 | 1924 | |
| 84 | Mike Cuellar | 7.50 | 1969 | |
| 84 | Hod Eller | 7.50 | 1919 | |
| 84 | George Earnshaw | 7.50 | 1931 | |
| 91 | Greg Maddux# | 7.48 | 2000 | |
| 92 | Roger Clemens# | 7.41 | 1986 | |
| 93 | Dave McNally | 7.40 | 1971 | |
| 93 | Randy Johnson# | 7.40 | 1999 | |
| 95 | Orval Overall | 7.36 | 1908 | |
| 95 | Jack Billingham | 7.36 | 1972 | |
| 95 | Gary Nolan | 7.36 | 1970 | |
| 95 | Alex Fernandez# | 7.36 | 1998 | |
| 99 | Jack Sanford | 7.33 | 1962 | |
| 100 | Aaron Sele# | 7.23 | 1998 |
