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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | WPCT | YEAR | Open Career Leaderboard |
|---|---|---|---|---|
| 1 | Johnny Allen | .938 | 1937 | |
| 2 | Al Spalding* | .917 | 1875 | |
| 3 | Cherokee Fisher | .909 | 1872 | |
| 4 | Kevin Appier# | .903 | 1991 | |
| 5 | Roger Clemens# | .897 | 1992 | |
| 6 | Pat Combs# | .895 | 1991 | |
| 7 | Ron Guidry | .893 | 1978 | |
| 8 | Lefty Grove* | .886 | 1931 | |
| 8 | Pedro Martinez# | .886 | 1992 | |
| 10 | Jack Manning | .882 | 1875 | |
| 11 | Preacher Roe | .880 | 1951 | |
| 12 | Fred Goldsmith | .875 | 1880 | |
| 12 | Tom Seaver* | .875 | 1981 | |
| 14 | Joe Wood | .872 | 1912 | |
| 15 | Orel Hershiser | .864 | 1985 | |
| 15 | Pedro Martinez# | .864 | 1993 | |
| 17 | Bill Donovan | .862 | 1907 | |
| 17 | Whitey Ford* | .862 | 1961 | |
| 19 | Roger Clemens# | .857 | 1986 | |
| 19 | Mike Nagy | .857 | 1969 | |
| 19 | Dwight Gooden# | .857 | 1985 | |
| 22 | Sterling Hitchcock# | .852 | 1997 | |
| 23 | Charles Bender* | .850 | 1914 | |
| 24 | Randy Johnson# | .848 | 1999 | |
| 24 | Lefty Grove* | .848 | 1930 | |
| 26 | Terry Mulholland# | .846 | 2000 | |
| 26 | Preacher Roe | .846 | 1952 | |
| 28 | Tom Hughes | .842 | 1916 | |
| 28 | Emil Yde | .842 | 1924 | |
| 28 | Ralph Terry | .842 | 1961 | |
| 28 | Schoolboy Rowe | .842 | 1940 | |
| 32 | Alex Fernandez# | .840 | 1998 | |
| 33 | Lefty Gomez* | .839 | 1934 | |
| 34 | Bill Hoffer | .838 | 1895 | |
| 34 | Denny McLain | .838 | 1968 | |
| 36 | Walter Johnson* | .837 | 1913 | |
| 37 | King Cole | .833 | 1910 | |
| 37 | Spud Chandler | .833 | 1943 | |
| 37 | Aaron Sele# | .833 | 1998 | |
| 37 | Hoyt Wilhelm* | .833 | 1952 | |
| 37 | Sandy Koufax* | .833 | 1963 | |
| 37 | John Tudor | .833 | 1992 | |
| 43 | Charley Radbourn* | .831 | 1884 | |
| 44 | Roger Clemens# | .828 | 1989 | |
| 44 | Roger Clemens# | .828 | 1991 | |
| 46 | Elmer Riddle | .826 | 1941 | |
| 46 | Al Spalding* | .826 | 1872 | |
| 46 | Aaron Sele# | .826 | 1999 | |
| 46 | Ed Reulbach | .826 | 1906 | |
| 46 | Tom Glavine# | .826 | 1993 | |
| 51 | Dazzy Vance* | .824 | 1924 | |
| 51 | Bob Moose | .824 | 1969 | |
| 51 | Wayne Simpson | .824 | 1970 | |
| 51 | Jay Hughes | .824 | 1899 | |
| 51 | Al Orth | .824 | 1899 | |
| 51 | Jack Chesbro* | .824 | 1902 | |
| 57 | Bob Purkey | .821 | 1962 | |
| 57 | Doug Drabek# | .821 | 1994 | |
| 57 | Charles Bender* | .821 | 1910 | |
| 60 | Dave Stewart | .818 | 1988 | |
| 60 | Rick Aguilera | .818 | 1988 | |
| 60 | Pedro Martinez# | .818 | 1998 | |
| 60 | Sal Maglie | .818 | 1950 | |
| 64 | Greg Maddux# | .815 | 1993 | |
| 64 | Kenny Rogers# | .815 | 1995 | |
| 66 | Joe McGinnity* | .814 | 1904 | |
| 67 | Russ Ford | .812 | 1910 | |
| 67 | Mordecai Brown* | .812 | 1906 | |
| 67 | Moose Haas | .812 | 1983 | |
| 67 | Hooks Wiltse | .812 | 1904 | |
| 67 | Eddie Plank* | .812 | 1912 | |
| 67 | Carl Hubbell* | .812 | 1936 | |
| 73 | Dizzy Dean* | .811 | 1934 | |
| 74 | Ed Reulbach | .810 | 1907 | |
| 74 | Doc Crandall | .810 | 1910 | |
| 74 | Johnny Allen | .810 | 1932 | |
| 74 | Ted Wilks | .810 | 1944 | |
| 74 | Phil Niekro* | .810 | 1982 | |
| 79 | Larry Jansen | .808 | 1947 | |
| 79 | Tiny Bonham | .808 | 1942 | |
| 79 | Alvin Crowder | .808 | 1928 | |
| 79 | Denny Neagle# | .808 | 2000 | |
| 79 | Dave McNally | .808 | 1971 | |
| 79 | Catfish Hunter* | .808 | 1973 | |
| 79 | Bobo Newsom | .808 | 1940 | |
| 86 | Howie Camnitz | .806 | 1909 | |
| 86 | Dave Ferriss | .806 | 1946 | |
| 86 | Juan Marichal* | .806 | 1966 | |
| 86 | Christy Mathewson* | .806 | 1909 | |
| 86 | Pedro Martinez# | .806 | 2000 | |
| 86 | Eddie Cicotte | .806 | 1919 | |
| 92 | Bert Humphries | .800 | 1913 | |
| 92 | Sam Leever | .800 | 1905 | |
| 92 | Steve Avery# | .800 | 1995 | |
| 92 | Fernando Valenzuela | .800 | 1996 | |
| 92 | Stan Coveleski* | .800 | 1925 | |
| 92 | Ed Lopat | .800 | 1953 | |
| 92 | Sid Fernandez | .800 | 1991 | |
| 92 | John Smiley# | .800 | 1995 | |
| 92 | Hal Jeffcoat | .800 | 1956 |
