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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | SO | YEAR | Open Career Leaderboard |
|---|---|---|---|---|
| 1 | Jay Buhner | 192 | 1997 | |
| 2 | Mark McGwire# | 191 | 2000 | |
| 3 | Bobby Bonds | 189 | 1970 | |
| 4 | Rob Deer | 188 | 1991 | |
| 5 | Bobby Bonds | 187 | 1969 | |
| 5 | Andres Galarraga# | 187 | 1998 | |
| 5 | Sammy Sosa# | 187 | 1996 | |
| 8 | Rob Deer | 186 | 1987 | |
| 9 | Pete Incaviglia | 185 | 1986 | |
| 10 | Andres Galarraga# | 183 | 1997 | |
| 11 | Jose Canseco# | 182 | 1998 | |
| 12 | Phil Plantier# | 181 | 1999 | |
| 13 | Mike Schmidt* | 180 | 1975 | |
| 14 | Rob Deer | 179 | 1986 | |
| 15 | Bo Jackson# | 178 | 1996 | |
| 16 | Phil Plantier# | 176 | 1993 | |
| 17 | Doug Jennings | 175 | 1997 | |
| 17 | Dave Nicholson | 175 | 1963 | |
| 17 | Jose Canseco# | 175 | 1986 | |
| 17 | Gorman Thomas | 175 | 1979 | |
| 17 | Greg Vaughn | 175 | 1988 | |
| 22 | Bo Jackson# | 174 | 1997 | |
| 23 | Jim Presley | 172 | 1986 | |
| 23 | Bo Jackson# | 172 | 1998 | |
| 25 | Reggie Jackson* | 171 | 1968 | |
| 26 | Jim Thome# | 170 | 1999 | |
| 26 | Jay Buhner | 170 | 1998 | |
| 26 | Gorman Thomas | 170 | 1980 | |
| 29 | Jose Canseco# | 169 | 1999 | |
| 29 | Mark Bellhorn# | 169 | 1997 | |
| 31 | Mark Bellhorn# | 168 | 1998 | |
| 31 | Juan Samuel | 168 | 1984 | |
| 31 | Bob Hamelin# | 168 | 1988 | |
| 31 | Nick Esasky | 168 | 1988 | |
| 31 | Pete Incaviglia | 168 | 1987 | |
| 36 | Ray Martinez# | 166 | 1997 | |
| 36 | Steve Balboni | 166 | 1985 | |
| 36 | Bo Jackson# | 166 | 1993 | |
| 36 | Gary Alexander | 166 | 1978 | |
| 36 | Cory Snyder | 166 | 1987 | |
| 36 | Luis Medina | 166 | 1991 | |
| 42 | Jose Hernandez# | 165 | 2000 | |
| 42 | Bo Jackson# | 165 | 1988 | |
| 42 | Dean Palmer# | 165 | 1996 | |
| 42 | Jose Canseco# | 165 | 2000 | |
| 46 | Preston Wilson# | 163 | 1999 | |
| 46 | Sammy Sosa# | 163 | 2000 | |
| 46 | Donn Clendenon | 163 | 1968 | |
| 46 | Jose Valentin# | 163 | 1996 | |
| 50 | Rob Deer | 162 | 1988 | |
| 50 | Juan Samuel | 162 | 1987 | |
| 50 | Rob Deer | 162 | 1990 | |
| 50 | Butch Hobson | 162 | 1977 | |
| 50 | Greg Vaughn | 162 | 1997 | |
| 55 | Dick Allen | 161 | 1968 | |
| 55 | Phil Plantier# | 161 | 1995 | |
| 55 | Reggie Jackson* | 161 | 1971 | |
| 55 | Troy Neel | 161 | 1998 | |
| 55 | Bo Jackson# | 161 | 1999 | |
| 55 | Lee Stevens# | 161 | 1998 | |
| 61 | Ron Gant# | 160 | 1996 | |
| 61 | Dean Palmer# | 160 | 1992 | |
| 61 | Rico Brogna# | 160 | 1998 | |
| 61 | Ruben Rivera# | 160 | 1998 | |
| 61 | Rob Deer | 160 | 1989 | |
| 61 | Sammy Sosa# | 160 | 1995 | |
| 67 | Jose Hernandez# | 159 | 1999 | |
| 67 | Troy Neel | 159 | 1995 | |
| 67 | Bo Jackson# | 159 | 1989 | |
| 67 | Danny Tartabull | 159 | 1995 | |
| 67 | Jay Buhner | 159 | 1995 | |
| 72 | Preston Wilson# | 158 | 2000 | |
| 72 | Patrick Lennon# | 158 | 1992 | |
| 72 | Bo Jackson# | 158 | 1987 | |
| 72 | Sammy Sosa# | 158 | 1997 | |
| 76 | Jose Canseco# | 157 | 1987 | |
| 76 | Russell Branyan# | 157 | 2000 | |
| 76 | Fred McGriff# | 157 | 2000 | |
| 76 | Jim Presley | 157 | 1987 | |
| 76 | Greg Vaughn | 157 | 1998 | |
| 76 | Danny Tartabull | 157 | 1986 | |
| 76 | Sammy Sosa# | 157 | 1998 | |
| 76 | Andres Galarraga# | 157 | 1991 | |
| 84 | Jim Thome# | 156 | 2000 | |
| 84 | Tony Armas | 156 | 1984 | |
| 84 | Dave Kingman | 156 | 1982 | |
| 84 | Andres Galarraga# | 156 | 1999 | |
| 84 | Reggie Jackson* | 156 | 1982 | |
| 84 | Phil Plantier# | 156 | 1992 | |
| 84 | Tommie Agee | 156 | 1970 | |
| 84 | Patrick Lennon# | 156 | 1993 | |
| 84 | Delino DeShields# | 156 | 2000 | |
| 84 | Sammy Sosa# | 156 | 1994 | |
| 94 | Cecil Fielder | 155 | 1996 | |
| 94 | Jeff Burroughs | 155 | 1975 | |
| 94 | Frank Howard | 155 | 1967 | |
| 94 | Andres Galarraga# | 155 | 1989 | |
| 94 | Cecil Fielder | 155 | 1988 | |
| 94 | Eric Davis# | 155 | 1996 | |
| 100 | Juan Samuel | 154 | 1988 |
