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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | SO | YEAR | Open Career Leaderboard |
|---|---|---|---|---|
| 1 | Rob Deer | 188 | 1991 | |
| 2 | Sammy Sosa# | 187 | 1996 | |
| 3 | Rob Deer | 186 | 1987 | |
| 4 | Jose Canseco# | 175 | 1986 | |
| 4 | Dave Nicholson | 175 | 1963 | |
| 6 | Pete Incaviglia | 168 | 1987 | |
| 7 | Luis Medina | 166 | 1991 | |
| 8 | Sammy Sosa# | 163 | 2000 | |
| 9 | Greg Vaughn | 162 | 1997 | |
| 9 | Rob Deer | 162 | 1988 | |
| 9 | Rob Deer | 162 | 1990 | |
| 12 | Dick Allen | 161 | 1968 | |
| 12 | Troy Neel | 161 | 1998 | |
| 14 | Rico Brogna# | 160 | 1998 | |
| 14 | Rob Deer | 160 | 1989 | |
| 16 | Sammy Sosa# | 158 | 1997 | |
| 16 | Bo Jackson# | 158 | 1987 | |
| 18 | Jose Canseco# | 157 | 1987 | |
| 18 | Russell Branyan# | 157 | 2000 | |
| 18 | Greg Vaughn | 157 | 1998 | |
| 18 | Sammy Sosa# | 157 | 1998 | |
| 22 | Frank Howard | 155 | 1967 | |
| 23 | Willie Stargell* | 154 | 1971 | |
| 24 | Russell Branyan# | 153 | 1997 | |
| 24 | Dave Kingman | 153 | 1975 | |
| 26 | Russell Branyan# | 152 | 1998 | |
| 26 | Shane Mack# | 152 | 1997 | |
| 28 | Rico Brogna# | 151 | 1999 | |
| 28 | Greg Luzinski | 151 | 1975 | |
| 30 | Ron Kittle | 150 | 1983 | |
| 31 | Rob Deer | 147 | 1992 | |
| 32 | Karl Rhodes# | 145 | 1996 | |
| 33 | Dave Kingman | 143 | 1977 | |
| 33 | John Vander Wal# | 143 | 1991 | |
| 33 | Byron Browne | 143 | 1966 | |
| 33 | Alfonso Soriano# | 143 | 1999 | |
| 37 | Harmon Killebrew* | 142 | 1962 | |
| 37 | Eric Davis# | 142 | 1994 | |
| 39 | Delino DeShields# | 141 | 1995 | |
| 39 | Mike Simms# | 141 | 1995 | |
| 39 | Andy Van Slyke | 141 | 1990 | |
| 39 | Greg Vaughn | 141 | 1994 | |
| 39 | Frank Howard | 141 | 1968 | |
| 39 | Jeff Conine# | 141 | 1989 | |
| 45 | Greg Luzinski | 140 | 1977 | |
| 45 | Derek Bell# | 140 | 1998 | |
| 47 | Troy Neel | 139 | 1997 | |
| 47 | John Vander Wal# | 139 | 1993 | |
| 49 | Luis Medina | 138 | 1990 | |
| 49 | Brad Wilkerson# | 138 | 2000 | |
| 49 | Sammy Sosa# | 138 | 1999 | |
| 49 | Doug Jennings | 138 | 1990 | |
| 49 | George Foster | 138 | 1978 | |
| 54 | Rico Brogna# | 137 | 1996 | |
| 54 | Ron Kittle | 137 | 1984 | |
| 54 | Derek Bell# | 137 | 1997 | |
| 54 | David Justice# | 137 | 1997 | |
| 54 | Shane Mack# | 137 | 1996 | |
| 59 | Harmon Killebrew* | 135 | 1964 | |
| 59 | Greg Luzinski | 135 | 1978 | |
| 59 | Greg Luzinski | 135 | 1973 | |
| 59 | Rico Brogna# | 135 | 1997 | |
| 63 | Andy Van Slyke | 134 | 1991 | |
| 63 | Vince Coleman | 134 | 1988 | |
| 63 | Lou Brock* | 134 | 1966 | |
| 63 | Phil Bradley | 134 | 1986 | |
| 67 | John Vander Wal# | 133 | 1994 | |
| 67 | Dave McCarty# | 133 | 1998 | |
| 69 | Karl Rhodes# | 132 | 1995 | |
| 69 | Al Martin | 132 | 1996 | |
| 71 | Andy Van Slyke | 131 | 1988 | |
| 71 | Brian Jordan# | 131 | 1997 | |
| 71 | Dave Kingman | 131 | 1979 | |
| 74 | Derek Bell# | 130 | 1991 | |
| 75 | Willie Stargell* | 129 | 1973 | |
| 75 | Howard Johnson | 129 | 1991 | |
| 75 | Phil Bradley | 129 | 1985 | |
| 78 | Moises Alou# | 128 | 1989 | |
| 78 | Greg Vaughn | 128 | 1992 | |
| 78 | Doug Jennings | 128 | 1993 | |
| 81 | Willie Stargell* | 127 | 1965 | |
| 81 | Corey Patterson# | 127 | 2000 | |
| 81 | Tommy Harper | 127 | 1965 | |
| 81 | Lou Brock* | 127 | 1964 | |
| 81 | Sherman Obando# | 127 | 1993 | |
| 81 | Chet Ross | 127 | 1940 | |
| 87 | Vince Coleman | 126 | 1987 | |
| 87 | Dave Nicholson | 126 | 1964 | |
| 87 | Jay Buhner | 126 | 1996 | |
| 87 | Danny Walton | 126 | 1970 | |
| 87 | Lee Tinsley# | 126 | 2000 | |
| 87 | Jim Rice* | 126 | 1978 | |
| 93 | Frank Howard | 125 | 1970 | |
| 93 | Manny Ramirez# | 125 | 1997 | |
| 93 | Tim Salmon# | 125 | 1996 | |
| 96 | Lou Brock* | 124 | 1968 | |
| 96 | Candy Maldonado | 124 | 1988 | |
| 96 | Lee Stevens# | 124 | 1996 | |
| 99 | Eric Davis# | 123 | 1992 | |
| 99 | George Foster | 123 | 1982 |
